Principal Scientist / County Durham / £35,385- £49,750 (dependent upon experience)
Kelly Scientific are working alongside a global leader within Biopharmaceuticals on their search for 3 Principal Scientists to be based at their state-of-the-art facilities in the North East.
Highly motivated individuals are sought to join a group of scientists working to develop recombinant protein processes suitable for the manufacture of biotherapeutics. The available positions are for Principal Scientists based on qualifications and experience in executing and initially developing one of the following: analytical methods, mammalian cell culture or protein purification.
The successful candidates will be laboratory-based and, working as part of project teams:
- Analytical Development: Involved in the transfer, establishment, development, and qualification of analytical methods associated with the assessment and characterisation of recombinant proteins, including techniques such as chromatography, electrophoresis, and spectroscopy. Providing analytical support to both upstream and downstream process development. Facilitating transfer of analytical methods to Quality Control.
- Upstream Mammalian Cell Culture: Involved in cell line development (CLD; from transfection, cloning and selection of cell lines to evaluation of clonal cell lines in scale-down mimics of the production process) and / or process development (PD; from scale down mimics to pilot scale bioreactors), dependent on experience. Future opportunities to be cross trained in microbial fermentation also exist.
- Downstream Processing: Involved in the design, establishment and development of downstream protein purification processes to capture, enrich and purify a plethora of molecular classes pertinent to the biopharmaceutical and healthcare industry from a range of expression systems such as microbial and mammalian feedstocks.
Education & Experience
- Principal Scientist: PhD with/without post-doctoral study-level or equivalent relevant biotech/pharmaceutical industry experience within the areas advertised
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