Senior Scientist - In vivo
London - on site at the Francis Crick institute
LifeArc is an independent life science medical research charity committed to drastically improving positive patient outcomes everywhere. As a champion for human health, LifeArc partners with academic, biotechnology, pharmaceutical, and charity organisations to move promising medical research forward into viable and accessible patient treatments. As a charity we are self-funded, re-investing our income from developed drugs and diagnostics to support translating research from the bench to patient. We are pioneering new ways to turn great science into greater patient impact.
We are currently seeking a highly motivated and well organised Senior Scientist - In vivo to join our expanding Antibody Discovery team at LifeArc. The position will be based at the Francis Crick Institute in London, but you will be working very closely with Scientists within our Centre for Therapeutics Discovery in Stevenage.
You will be primarily responsible for ethically managing our transgenic mouse colonies housed within the Biological Research Facility (BRF) at the Francis Crick institute. You will also be responsible for designing and performing antibody discovery projects from immunisation to immune tissue preparation for B-cell sorting experiments to support various LifeArc projects. You will also be responsible for supporting numerous immunisation campaigns, ensuring the smooth transition of projects between LifeArc and the Francis Crick Institute and interacting very closely with both the BRF and FACS Science Technology Platforms at the Crick, as well as other project team members based at our Stevenage site.
Who you are
You will have over five years practical lab experience in a Pharmaceutical, Biotech or Contract Research Organization, or laboratory environment working directly with small animals (rodents) and mammalian cell culture. You will be PhD qualified in biological science or related discipline, or MSc with equivalent experience with a strong emphasis on immunology. You will have experience in immunisation protocols including antigen, whole cells, and HDTV DNA methods. You will have experience in creating/editing/training others with Standard Operating Procedures. You will possess team leading and project management skills. You will hold an HO personal licence and will act as deputy project licence holder and as such should be able to perform procedures described in the project licence. Knowledge of flow cytometry standards, protocols and best practices is advantageous
Your salary will be determined by qualifications and experience. In addition, LifeArc offers a defined contribution pension scheme, private health insurance, a flexible benefits scheme and 31 days paid holiday per year.
LifeArc is committed to the principles and practices of equal opportunities and to encouraging the establishment of a diverse workforce. It is our policy to employ individuals on the basis of their suitability for the work to be performed and their potential for development, regardless of age, sex, race, colour, nationality, ethnic or national origin, disability, marital status, pregnancy or maternity, sexual orientation, gender reassignment, religion or belief. This includes creating a culture that fully reflects our commitment to equal opportunities for all.
To apply please email your CV and covering letter explaining why you want to work for LifeArc to: or by post to Recruitment, LifeArc, Accelerator Building, Open Innovation Campus, Stevenage, SG1 2FX (electronic applications preferred).
Closing Date - Friday 20th November 2020
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As an Equal Opportunities employer we welcome applications from all suitably qualified persons regardless of their race, sex, disability, religion/belief, sexual orientation or age.